But Herrera was dismissed for two fouls on Eden Hazard following what looked like an edict to target the Belgium playmaker.
Chelsea eventually broke the deadlock after 51 minutes as N'Golo Kante was afforded space and he drilled the ball home from 20-yards out.
With Zlatan Ibrahimovic suspended and injuries to Anthony Martial and Wayne Rooney, Rashford's illness meant Jose Mourinho might have been deprived of a recognised striker at his former stomping ground of Stamford Bridge.
The two English powerhouses meet in the FA Cup quarterfinals for the latest chapter of a rivalry given added spice by the fact that Conte was eventually appointed as the permanent successor to the sacked Mourinho at Chelsea.
Patty Mills scores 21 points as Spurs crush Warriors
The San Antonio Spurs will have to try and erase a 1.5-game deficit on Golden State without the services of LaMarcus Aldridge. Golden State is crossing their fingers that he will be able to return to the court in the early stages of the postseason.
"You're not special anymore", sang Chelsea fans, between expletive-filled chants directed at the self-styled "Special One". United were routed 4-0 at Stamford Bridge.
Well played, Jose. Chelsea's best years in the Premier League arguably came during Mourinho's reign, so for their fans to abuse him is disrespectful.
The Portuguese boss has made it no secret that Shaw is behind his team-mates in the pecking order and must take inspiration from Henrikh Mkhitaryan who has forced his way into Mourinho's plans.
United: De Gea, Valencia, Jones, Smalling, Rojo, Darmian, Herrera, Pogba, Young, Mkhitaryan, Rashford. Manchester United have been unbeaten in all competitions since November 2016.
Toyota stolen with 4-year-old girl inside
Police said the vehicle may have been abandoned when the child was discovered inside and are concerned for her safety. The auto , a 2008 Toyota Camry with the licence plate BHVH392, was later seen near Highway 401 and Highway 403.
Joining them are Arsenal, Tottenham and Manchester City, who all cruised into the FA Cup semi-finals with wins over Lincoln City, Millwall and Middlesbrough respectively.
United lucky to finish this game with 10 men, let alone 11.
It's been a bit more of a roller-coaster for José Mourinho at Manchester United, but his Red Devils captured the EFL Cup and are still in the Europa League.
Two men attack commuters with axe at Dusseldorf rail station
The attack happened around 9 p.m. local time at the main train station in Düsseldorf, according to federal police in Germany. German newspaper Bild reported that two suspect has been taken into custody and that two other suspects were on the loose.